Bookcover of Identification of EBNA binding cellular proteins
Booktitle:

Identification of EBNA binding cellular proteins

Identification of EBNA binding cellular proteins using the yeast two hybrid system

LAP LAMBERT Academic Publishing (2012-04-22 )

Books loader bb69257a3a9a387d440a41825df873e80c07784fb50385ca6925e0245e5555d7

Omni badge 9307e2201e5f762643a64561af3456be64a87707602f96b92ef18a9bbcada116 eligible for voucher
ISBN-13:

978-3-8484-8877-3

ISBN-10:
3848488779
EAN:
9783848488773
Book language:
English
Blurb/Shorttext:
Epstein-Barr virus (EBV) is a common herpesvirus that establishes life-long persistence in the human host through the elaborate regulation of different latency types. Latent EBV infection of resting B cells converts them into transformed cells that can develop into tumors in immune-compromised hosts. As such, EBV infection is a unique, well-defined in vitro system for malignant transformation. The latency-associated EBV proteins are the key factors for virus-induced cell transformation. To fully understand the molecular mechanisms that lead to virusinduced transformation, the cellular targets of the transforming viral proteins have to be identified. During the work summarized in this thesis, the following EBV encoded nuclear antigen (EBNA) binding proteins were identified: -subunit of the human chaperonin TCP-1 complex; XAP2, the minor subunit of the arylhydrocarbon receptor (AhR) complex; a novel human uridine kinase/uracilphosphoribosyltransferase (for EBNA-3); and p14ARF (for EBNA-5).
Publishing house:
LAP LAMBERT Academic Publishing
Website:
http://www.lap-publishing.com/
By (author) :
Elena Kashuba
Number of pages:
56
Published on:
2012-04-22
Stock:
Available
Category:
Monographies
Price:
3854.22 руб
Keywords:
Epstein-Barr Virus, Protein-Protein Interaction, EBNA, yeast two-hybrid system

Books loader bb69257a3a9a387d440a41825df873e80c07784fb50385ca6925e0245e5555d7

Newsletter

Wire Transfer

  0 products in the shopping cart
Edit cart
Loading frontend a1511bff1b5d307157b6d2998f00204b5e7a82a6a02fd75b149775d94b377442
LOADING